欧盟食品安全局就食品中的硝基呋喃及其代谢物发布意见

      据欧盟食品安全局（EFSA）消息，6月26日欧盟食品安全局就食品中的硝基呋喃及其代谢物发布意见。本次欧盟食品安全局评估了呋喃唑酮、呋喃它酮、呋喃咀啶、呋喃西林以及硝呋索尔类硝基呋喃。目前欧盟禁止硝基呋喃类抗菌剂用于产肉动物。然而呋喃唑酮、呋喃咀啶与呋喃西林可以用于人类。

    欧盟食品安全局污染物专家组建议，根据目前的指南有必要开展SEM的致癌性研究，有必要了解SEM遗传毒性与致癌效应的机理。

    部分原文报道如下：

    Nitrofurans are antimicrobial agents not authorised for use in food-producing animals in the European Union. Nitrofurans are rapidly metabolised, occurring in animal tissues as protein-bound metabolites. The European Commission requested EFSA to provide a scientific opinion on the risks to human health related to the presence of nitrofurans in food and whether a reference point for action （RPA） of 1.0 ?g/kg for the marker metabolites is adequate to protect public health. Data on occurrence of nitrofuran marker metabolites in food were extracted from the national residue monitoring plan results and from the Rapid alert System for Food and Feed （RASFF）。 The ConTAM Panel concluded that these data were too limited to carry out a reliable human dietary exposure assessment. Instead, human dietary exposure was calculated for a scenario in which a single nitrofuran marker metabolite is present at 1.0 ?g/kg in foods of animal origin, excluding milk and dairy products.

    原文链接：http://www.efsa.europa.eu/en/efsajournal/doc/4140.pdf