欧盟发布转基因大豆A2704-12新测序信息的风险评估

　　  2018年11月26日，欧盟食品安全局（EFSA）发布关于转基因大豆A2704-12新测序信息的风险评估。

 

　　转基因生物（GMO）小组此前就转基因大豆A2704-12预期用途对人类和动物健康及环境影响做了风险评估，发现这种大豆与传统大豆和商业大豆品种一样安全和有营养。经过评估，新的测序数据和对新序列进行的生物信息学分析没有引起安全问题。因此，EFSA得出结论，大豆BPS - CV127 - 9的原始风险评估仍然有效。

 

　　部分原文报道如下：

 

　　The GMO Panel has previously assessed genetically modified （GM） soybean A2704‐12. This soybean was found to be as safe and nutritious as its conventional counterpart with respect to potential effects on human and animal health and the environment in the context of its intended uses. On 5 June 2018, the European Commission requested EFSA to analyse new nucleic acid sequencing data and updated bioinformatics data for GM soybean A2704‐12 and to indicate whether the previous conclusions of the GMO Panel on the risk assessment of GM soybean A2704‐12 remain valid. The new sequencing data indicated seven nucleotide differences as compared to the sequence originally provided in application EFSA‐GMO‐NL‐2005‐18; six nucleotides in the 3′ genomic flanking region and one nucleotide in the soybean chloroplast DNA fragment located 5′ to the insert. Another nucleotide located in a polylinker region of the insert reported as ambiguous in the originally submitted sequence was resolved in the new sequence data. based on the information provided on the locations affected by the reported nucleotide differences, no open reading frames （ORFs） spanning the junction site between the insert and the 3′ genomic flanking DNA are affected by the differences in the 3′ genomic flanking region and were therefore excluded from the assessment.